P20-06 Profile signatures of circulating miRNAs and contribution of organ-specific miRNAs in a mouse model chronically exposed to air pollution-derived ultrafine particles - École nationale supérieure Mines-Télécom Lille Douai Accéder directement au contenu
Proceedings/Recueil Des Communications Toxicology Letters Année : 2022

P20-06 Profile signatures of circulating miRNAs and contribution of organ-specific miRNAs in a mouse model chronically exposed to air pollution-derived ultrafine particles

E. Barbier
  • Fonction : Auteur
J. Carpentier
  • Fonction : Auteur
O. Simonin
  • Fonction : Auteur
M. Figeac
S. Anthérieu
  • Fonction : Auteur
L.Y. Alleman
E. Perdrix
J.-M. Lo Guidice
  • Fonction : Auteur
G. Garçon
  • Fonction : Auteur

Résumé

Indoor environmental exposure to pesticides has become one of the major concerns that might adversely affect human health and development. People spend most of their lifetime in enclosed indoor environments where they might inhale harmful toxic chemicals, such as pesticides, dispersed either in particulate or in a gas phase. In this study, an assessment of pesticide contamination in indoor environments was conducted. The study covered nine houses during one year, starting from February 2016 and ending in February 2017, in which both air and dust samples were assessed for their potential contamination with 50 pesticides. The results showed that all the assessed houses were contaminated by several pesticides, especially with the allethrin pesticide (detection frequency (DF) = 100%). The highest pesticide contamination was detected in the spring/summer season when it reached an average of around 185 ng g−1 and 186.4 ng sampler−1 in the collected dust and air samples, respectively. The potential contamination of pyrethroid insecticides within all the targeted samples revealed by this study stresses the importance of minimizing the use of such indoor treatments as part of the efficient prevention and control of human exposure to pesticides.
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Dates et versions

hal-04138496 , version 1 (23-06-2023)

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Citer

E. Barbier, J. Carpentier, O. Simonin, M. Figeac, S. Anthérieu, et al.. P20-06 Profile signatures of circulating miRNAs and contribution of organ-specific miRNAs in a mouse model chronically exposed to air pollution-derived ultrafine particles. Toxicology Letters, 368 (21), pp.S252-S253, 2022, ⟨10.1016/j.toxlet.2022.07.672⟩. ⟨hal-04138496⟩
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